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Bestimmte Regionen und Teilregionen des assoziativen Kortex sind dementsprechend auf diese einzelnen visuellen Funktionen spezialisiert s.

Zeki, Meadows ; Pearlman et al. Hollins ; s. Kapitel 2. Aufgrund der Ergebnisse bei Menschen mit Blindsight geht man davon aus, dass das bewusste Sehen von Bewegungen sowohl ein intaktes Areal V1 als auch ein intaktes Areal V5 voraussetzt.

Alternatively, whatever operations V5 may undertake, the results of that operation must be re- entered into V1. Im Bereich der Sehnervkreuzung zweigen vielmehr einige Fasern vom Sehnerv ab.

Eine noch kleinere Anzahl von Nervenbahnen soll ebenfalls subkortikal zu einer anderen Struktur des Stammhirns verlaufen, der pretektalen Region.

Beide subkortikalen Bahnen werden auch als tectopulvinare Verbindungen bezeichnet vgl. Milz ; Hollins ; s. Singer , S. Obwohl die Hirnforschung schon seit ca.

Fragen wann, wie und wo wir uns bewusst werden ein Objekt zu sehen, wie sensorische Impulse z. Milz Lauber ; Hoyt, Kommerell ; Savino et al.

Zihl, Cramon Lediglich hochgradiger Visusverlust, zerebrale Achromatopsien oder Verluste des Tiefensehens bilden hier die Ausnahme vgl.

Cramon, Zihl , S. Schnabel, Sentker Lissauer unterscheidet zwei Formen der visuellen Objektagnosie: a apperzeptive visuelle Agnosie vgl.

Mawatari et al. Nach Zihl und Cramon , S. Auf der rechten Seite zeigen sich Schwierigkeiten selbst einfache Formen nachzuzeichnen.

Quelle: Zeki , S. Kawahata et al. Die Schwierigkeiten manifestieren sich vielmehr bei der Interpretation der Bedeutung von Formen.

Ein Patient, von dem Zeki , S. Pratesi et al. Zuvor wurde es entweder der Objektagnosie oder der Seelenblindheit zugeordnet Wilbrand ; Heidenhain bzw.

Gerard et al. Manchmal kann ein Patient auch verschiedene Gesichter unterschieden. Ein Patient konnte z. Quelle Zeki , S.

Es gibt kein einheitliches Erscheinungsbild von Patienten mit Farbagnosie. Brown Sie wurden zuerst von Poppelreuter systematisch untersucht.

Lenz , Gelb und H. Lenz beschrieben. Marx et al ; Barbizet et al. Die Schwierigkeiten zeigen sich vor allem beim Kopieren von einfachen geometrischen Figuren oder beim freien Zeichnen.

Critchley Heilman, van den Abell bzw. DeRenzi , negelect of one half of external space oder Hemineglect vgl. Crick , um das Syndrom zu beschreiben.

So kann es z. Befindet sich jedoch gleichzeitig irgendetwas Bemerkenswertes auf der anderen Seite, kann es sein, dass das Objekt auf der linken Seite nicht mehr gesehen wird.

Nach Crick kann Hemineglekt nicht nur bei der visuellen Wahrnehmung, sondern auch bei der visuellen Vorstellung auftreten.

Cogan, Adams bezeichnet. Hartmann Allerdings merken Zihl und Cramon , S. Babinsky ; Poetzl ; Barkman McDaniel, McDaniel Es wurde nach Anton benannt, der eine Frau beschrieb, die ihre Blindheit nicht bemerkte.

Beck et al. Hartmann et al. Walsh, Hoyt Sie lassen sich je nach Schweregrad, ihrer Lage, Form und Ausdehnung einteilen.

Tabelle 1. Jan, Groenveld ; s. Foley, Gordon ; Merrill, Kewman ; Ronen et al. Gloning, Tschabitscher ; Ritter et al. Alexandridis et al.

Unterschiedliche Begrifflichkeiten entstehen jedoch, indem einige vgl. Baillet et al. Pschyrembel , S. Foley, Gordon ; Merrill, Kewman ; Celesia et al.

Auch Ronen et al. Barnet et al. Weiskrantz et al. Ter Braak et al. Denny- Brown, Chambers ; Keating Obwohl sie behaupteten, dass ein solcher Versuch aussichtslos sei, stellte sich heraus, dass sie mit einer erstaunlich hohen Trefferquote die verschiedenen Richtungen der Stimuli auseinander halten konnten.

Auch dieser Patient versicherte ihm, ebenso wie die anderen Betroffenen, nichts zu sehen, sondern lediglich zu raten, obwohl er eine Vielzahl visueller Reize auseinander halten konnte vgl.

Campion et al. Nach Stoerig und Cowey , S. Stoerig et al. Weiskrantz ; Morland et al. Blythe et al. Barbur et al. Stoerig ; Stoerig, Cowey ; Brent et al.

Perenin et al. Obwohl auch Perenin et al. Jan et al. Aufgrund dieser weiter gefassten Definition kann nach Jan et al. Henrich in der Literatur finden.

Hertz et al. Porro et al. Tabelle 2. Snelling et al. Aldrich et al. Casanova et al. Whiting et al. Hochstetler, Beals ; Gospe bis hin zu einem bzw.

Thomas, Troost ; Parry et al. Gjerris, Mellemgaard ; Prakash et al. Truwit et al. Antonellis et al. Grimes et al.

Ichikawa et al. Levavi et al. Lambert et al. Eldridge, Punt ; Singh bzw. Felber et al. Memon et al. Merimsky et al. Nakajo et al.

Chew bzw. Coughlin et al. Chew ; van Nieuwenhuizen, Willemse ; Wong ; Chen et al. Ceccaldi et al. Sadeh et al.

Ronen et al. Auch Good et al. Balzar et al. Kraus et al. Akute Kortikale Blindheit kann in kritischen Situationen, wie z.

Garty et al. Ein Hydrozephalus kann sowohl akute als auch chronische CVI verursachen vgl. Lorber ; Arroyo et al. Tabelle 3. Anton ; Gerlach et al.

Henrich Obwohl der Begriff der Blindheit auch heute noch von verschiedenen Autorinnen und Autoren verwendet wird, ist er aufgrund der verschiedenen Beobachtungen und Tests vgl.

Kapitel 3. Cytowic et al. Nieuwenhuys et al. Cytowic , S. Groenveld et al. In den Studien von Huo et al.

Von insgesamt 76 untersuchten Kindern, diagostizierten Lanners et al. Quelle: nach Lanners et al. Van Hof- van Duin et al. Sie setzen stattdessen korrektive Augenbewegungen ein, um ein Objekt zu fixieren.

Dieses Verhalten kann ebenfalls bei angeborener homonymer Hemianopsie beobachtet werden. Nystagmus Lanners et al.

Es ist daher wahrscheinlich, dass bei den Kindern, die einen Nystagmus aufweisen, zumindest kleine Teile des striaten Kortex erhalten geblieben sind.

Huo et al. Jan, Groenveld , S. Bei Huo et al. Kolobome im Zusammenhang mit CVI auftreten. Infolge koexistierender Verletzungen der Augen bzw.

Good et al. So konnten Lanners et al. Wong , S. Bei Groenveld et al. Lanners et al. Castano et al. Quelle: Lanners et al.

In der Studie von Huo et al. Wieser , S. Ahmed und Dutton berichten z. Es wird vermutet, dass das Ziel von Stimulationen immer darauf ausgerichtet ist, den visuellen Kortex zu stimulieren vgl.

Wenn Licht die Retina erreicht, entsteht eine photochemische Reaktion, welche die Nervenbahnen vom Auge erregt.

Diese Aktionspotentiale werden zum visuellen Kortex transportiert. Nach Jan et al. Daher vermuten Jan et al. Light gazing Jan et al.

Tso, La Piana ; Guerry et al. Desmond et al. Da alle drei Verhaltensweisen der Stimulation des visuellen Kortex dienen sollen vgl.

Auch bei Kindern mit Photophobien kann light gazing auftreten vgl. Bei Kindern mit starken Photophobien empfehlen Lanners et al.

Dadurch kann sich eine Art zentraler Photophobie entwickeln, die als "thalamic glare" bezeichnet wird. Der Thalamus spielt u.

Wiesel ; Groenveld ; Dutton et al. Porro et a. Nach Porro et al. Overlooking Jan et al. Bei Lanners et al.

Taylor et al. Nach Good et al. Jedem Kind sollte daher 18 Benton et al. Devinsky und Good et al.

Auch in der Studie von Jan et al. Die 2 Kinder von den 16 untersuchten Personen mit kortikaler Blindheit, die Dutton et al.

Einige Autoren vgl. Segrares et al. Rizzo, Hurtig Identifikation von Objekten Jan et al. Diese Kinder konnten z. Auch Kivlin , S.

Morse , S. Identifikation von Gesichtern Verschiedene Autoren vgl. Kivlin ; Whiting et al. Bei der Studie von Whiting et al.

Kivlin , S. Entfernungs- und Tiefenwahrnehmung Die Ergebnisse verschiedener Studien vgl. Abschnitt Identifikation von Objekten.

Kosslyn et al. Die Autorinnen und Autoren konnten dementsprechend bei mentalen visuellen Bildern keine Aktivierung des visuellen Kortex nachweisen vgl.

Rowe, Kahn nach Chatterjee, Southwood Chatterjee, Southwood , S. Chatterjee und Southwood , S. Auch Devinsky , S. Devinsky , S. Goldenberg et al.

Goldenberg ; Redlich, Bonvicini nach Goldenberg et al. Die Autoren gehen daher davon aus, dass die Verneinung der Blindheit dadurch entsteht, dass die betroffenen Personen ihre mentalen visuellen Bilder mit der realen Wahrnehmung verwechseln.

Die Ergebnisse von Goldenberg et al. In der Diskussion geht es vor allem um autistische Symptome wie z.

Humphries , S. Diagnostiziert wird Autismus jedoch aufgrund des Verhaltens und nach speziellen Kriterien. Ek et al. Jordan Internet Adresse; Garreau et al.

Fraiberg ; Gense, Gense Jordan Internet Adresse. Dzikowski , S. Solche Empfindungen werden durch Bewegungen im visuellen Feld und bei schnellen Bewegungen im peripheren Bereich hervorgerufen Flickering vgl.

Auch schauen sie Objekte oder Personen selten direkt an, auch wenn sie versuchen diese zu erreichen und schenken einem einzelnen Spielzeug mehr Aufmerksamkeit als einer breiten Auswahl von Spielzeugen vgl.

Frith ; Grandin ; Jordan, Riding Tabelle 5. Dutton et al. Ogden Munk unterscheidet die Seelenblindheit als Verlust der visuellen Vorstellung von der Rindenblindheit als Verlust der visuellen Wahrnehmung.

Stoerig und Cowey , S. Stoerig , S. WHO Die vorhandenen Registrierungen orientieren sich zudem an unterschiedlichen Definitionen von Blindheit bzw.

Pfau et al. Hochrechnungen angewiesen vgl. Die wichtigsten vorhandenen Angaben sollen im Folgenden kurz dargestellt werden.

Steinkuller , S. Foster, Gilbert ; Gilbert et al. Mai und dem Uganda In Uganda wurden zwischen und in Schulen und zwischen und in communities 44 Regionen insgesamt Kinder unter 15 Jahren untersucht.

Waddell Im Zeitraum zwischen Februar und Dezember konnten so 45 Kinder, die zwischen einem und sechs Jahren alt waren, beobachtet werden.

Olurin , S. Bei drei anderen Kindern manifestierte sich die kortikale Blindheit als Folge einer Enzephalitis und bei drei weiteren Kindern aufgrund von schweren Kopfverletzungen.

Das Alter der Betroffenen reichte von einem Monat bis zu 76 Jahren. Foster, Gilbert ; Eckstein et al.

Tirosh et al. Texas Williamson et al. Tielsch et al. Steinkuller et al. Jan, Robinson ; Jan et al. Nach der nordamerikanischen Definition wird partially seeing Sehbehinderung von Blindheit legally blind unterschieden.

Legally blind beschreibt dabei Kinder von einem Visus von 0,1 bis zum Fehlen von Lichtscheinwahrnehmung und umfasst damit einen wesentlich breiteren Bereich als der deutsche Begriff der Blindheit vgl.

Hudelmayer Mets , S. Schweden Am Dezember geboren wurden. Bei sechzehn Kindern wurde cortical blindness, bei neun Kindern cortical visual impairment, diagnostiziert vgl.

Ducrey et al. Estimation of visual function is difficult owing to communication problems: A Infants and young children deemed by refering clinicians to have poor vision.

B Multiply handicapped children. Bei Kindern bis zum Rath, Hudelmayer , S. In einer Studie von Hansen et al. Hansen et al.

Waddell ; Dandona et al. Meremikwu et al. Rosenberg et al. Kommt es im Zusammenhang mit CVI z. Da CVI meist mit mehrfachen Behinderungen s.

Einige Autorinnen und Autoren erfassen sowohl Kinder als auch Erwachsene vgl. Doch auch bei diesen Studien variiert das Altersspektrum deutlich.

So gibt es Autorinnen und Autoren vgl. Bayce, Alemayece , andere Kinder bis 9 Jahren vgl. Arnaud et al. Williamson et al.

Trosh et al. Dandona et al. Bohme, Tonnquvist Wesentlich geringer fallen die Populationen in der Untersuchung von Meremikwu et al.

Im VIP werden z. Trotz der differierenden Erhebungs- bzw. Foster, Gilbert ; Thylefors ; Eckstein et al.

Ferrell , Whiting et al. Seit ca. Robertson et al. Nach Wieser , S. Shibata et al. Yuen ; Kasahata et al. Psatta, Matei ; Lambert et al. DeVolder et al.

Price et al. Patronas, Argyopoulou , Embolien vgl. Heeney, Koo ; Acolovschi et al. Lebedeva, Kanevskaia ; Howard et al.

Tsutsui et al. Murayama et al. Sanin, Mathew ; Ogden ; Milandre et al. Man nimmt an, dass der zugrunde liegende Mechanismus Infarkte an den arteriellen Grenzzonen der Wasserscheidengebiete, den sogenannten parietookkipital und parasagittalen Regionen, sind vgl.

Volpe et al. Hoyt, Walsh ; Benton et al. Das Erscheinungsbild bzw. In den Untersuchungen von Flodmark et al.

Pape, Wigglesworth Casteels ; s. Shuman, Selednik ; Roland et al. Uggetti et al. Flodmark et al. So war auch in den Untersuchungen von Groenveld et al.

Hoyt, Walsh ; Weinberger et al. Casteels et al. Haas, Souner Griffith, Dodge ; Drymalski Auch Palinopsien 26 konnten beobachtet werden vgl.

Singh Der Sehverlust nach weniger schweren Traumata kann sich ca. Han, Wilkinson Tabelle 7. Hier manifestiert sich die Blindheit sofort oder innerhalb einiger Minuten nach dem Unfall.

Das adoleszente Muster, bei dem die Betroffenen zwischen 8 bis zu 14 Jahren alt sind, wird von Greenblatt als das Paradigma des Syndroms verstanden.

Gjerris und Mellemgaard betonen, dass Erwachsene wesentlich mehr verschiedene und schwerere Symptome haben.

Es kann sich dabei iktal Zung, Margalith ; Joseph, Louis oder postiktal vgl. Skolik et al. Kosnik et al.

Barry et al. Verdile, Verdile ; Chew ; Lau et al. Die Mehrheit der Betroffenen war zehn oder zwanzig Jahre alt, und der Sehverlust dauerte einige Minuten bis zu einer halben Stunde.

Der Sehverlust manifestierte sich entweder iktal oder postikatal. Postiktale Blindheit kann u.

Olurin ; Fiume Aldrich, Vanderzant Daher ist nach Good et al. Helmchen et al. Kinn, Breisblatt ; Kermode et al.

Horwitz, Wener ; Good et al. Wesentlich seltener wird es nach Aortographie vgl. Johnson, Moss 32 und nach Myelographie vgl. Smirniotopoulos et al.

Kinn, Breisblatt ; Rama et al. Studdard et al. Manifestation Der Sehverlust als Folge der Infusion von Kontrastmitteln manifestiert sich innerhalb von ein paar Minuten bis zu 12 Stunden nach einer Angiographie.

Fast alle Betroffenen regenerieren sich nach und nach innerhalb von zwei bis zu sieben Tagen vgl. Brewster et al. Lawrence et al.

Kabra et al. Waldron, Stallworth 36 oder als Komplikation einer Nephritis vgl. Devathasan et al.

Drymalski Ackroyd Tepperberg et al. Gado et al. Katafuchi et al. Es lassen sich auch Berichte von Neurotoxikosen nach einem Kobrabiss vgl.

Berger, Brook , einer Quecksilbervergiftung vgl. Davis et al. Gospe oder einer Toxoplasmose vgl.

Wilson et al. Cyclosporin-A, Interleukin 2 vgl. Cisplatin berichtet vgl. Higley et al. Das Kokain diffundiert sehr schnell durch die Plazentaschranke.

Dixon , S. Kupferschmidt et al. Craigen et al. Brown et al. Amano et al. Servidei et al. Kormguth et al.

Connolly et al. Hagerty et al. Mathe et al. Durand et al. Tsutsumi et al. Burke et al. Marsh, Hurst ; Hayashi et al.

Goldberg, Custis 52, Leigh-Syndrom vgl. Morris, Harbord ; Donovan ; Oldfors et al. MacDonald ; Markowitz et al.

Schonlein-Henoch Syndrom vgl. Benhamou et al. Schimmelpfennig-Feuerstein-Mims-Syndrom vgl. Hager 56, Creutzfeld-Jakob Krankheit Pinto et al.

Carney, Anderson a,b 58, Mumps vgl. Ohama et al. Hahn et al. Fanton et al. Payton, Jones 61, Multiple Sclerose vgl.

Castaigne et al. Constantinou et al. Assadi et al. Opitz et al. Ikeda et al. Elner et al. Sahota et al.

Es kann aber auch verschiedene neurodegenerative Erkrankungen z. Estbe ; Jin et al. Krimmel, Reinert ; Okamoto et al. Hydrozephalus kann akute, aber auch chronische CVI bedingen.

Corbett Sekhar et al. Hochwald, Sahar ; Saher Osher et al. Keane ; Drymalski , aber auch schwerer bilateraler Sehverlust kann beobachtet werden vgl.

Keen ; Wybar ; Jan et al. Der Sehverlust kann abrupt auftreten und von einer Reihe visueller Symptome begleitet werden vgl.

Hayreh und Okkipitalinfarkte aufgrund der Kompression der hinteren Zerebralarterie vgl. Arroyo et al.

Moore, Sterm Erstmals von zerebraler Blindheit in Folge einer Bestrahlung haben Pomeranz et al. In dieser haben sie drei Kinder untersucht.

Das Absterben eines Zwillings geschieht teilweise unbemerkt, so dass Good et al. Angeborene Hirnfehlbildungen s. Bei 14 Kindern waren die zerebralen Anomalien unspezifisch.

Barkovich, Norman a und der Abwesenheit des Septum Pellukidum vgl. Barkovich, Norman b verbunden. Barkovich et al. Fantz Teller et al.

Birch und Bane , S. McDonald et al. Good ; Jan et al. Allen et al. Meienberg et al. Das Suchmuster kann dann als grobes Muster benutzt werden, um das visuelle Feld zu messen vgl.

Van Hof-van Duin, Mohn Manchmal erlaubt auch ein Goldmann Perimeter ein genaues Messen des Gesichtsfeldes s.

Akiyama et al. Danach werden differente Elektroden, die in Kontaktlinsen eingearbeitet sind, auf die Hornhaut gesetzt.

Nickel, Hoyt Bei dieser Methode werden an der Kopfhaut der Patientinnen und Patienten Kontaktelektroden angebracht, die die Potentialschwankungen des Gehirns registrieren.

Der Alpharhythmus entwickelt sich im Alter von drei Monaten und stabilisiert sich mit dem ersten Lebensjahr.

Er wird durch psychosensorische Reizung z. Jan, Wong Ackroyd , Tepperberg et al. Bodis- Wollner et al. Reim , S. Kupersmith, Nelson Jan, Wong ; Whiting et al.

So stellten auch Whiting et al. Bowerman et al. Mohn et al. Von pathologischen Strukturen wie z. Weindling et al. PVL ist daher in der subakuten Phase mit Sonographie nur schwer zu diagnostizieren.

Bosley et al. Gottlob , S. Die visuellen Funktionen sollen sich bei diesen Kindern erst zwischen dem zweiten und vierten Lebensjahr verbessern.

Innerhalb der ersten zwei Jahre soll es bei dieser Gruppe zu einer Verbesserung des Visus kommen, selbst wenn die zugrundeliegende Augenkrankheit nicht behandelt werden kann.

Sie zeigen keine visuelle Aufmerksamkeit und fixieren oder folgen auch keinen hellen Objekten vgl. Lancet Fielder, Mayer ; Wieser Vielmehr konnten auch visuelle Antworten bei Kindern ohne visuellen Kortex beobachtet werden vgl.

Aylward et al. So beschreiben Aykward et al. Lambert Nach Flodmark et al. Smythies , S. Griffith, Dodge Drymalski ; Ramani ; Beck et al.

Faust Viele Kinder haben Schwierigkeiten mit ganz spezifischen visuellen Stimuli vgl. Morse , die sich z.

Daher kann nach Groenveld et al. Diese Faktoren werden daher mit bestimmten Prognoseaussichten verbunden. Dabei gehen Flodmark et al. Auch Lambert et al.

Wong ; Foley, Gordon ; Hoyt ; Wunderlich et al. Erwachsene mit erworbenem CVI vgl. Wong, ; Foley, Gordon , Wong ; Casteels et al.

Kennard ; Stewart, Riesen Janowsky, Finley ; Pilar et al. Blakemore Wunderlich et al. Der These von Tresidder et al.

Wong ; Foley, Gordon Wong So stellen van Hof- van Duin , S. Beneveto, Fallon ; Mauguiere, Ballydier Arnott ; Braddick et al.

Islands of preserved residual vision Andere Autorinnen und Autoren vgl. Kasten et al. Chow et al. Provis et al. Frotscher Internet Adresse.

Die Autorinnen und Autoren vermuten daher, ebenso wie Rausch et al. Baskin, Hosobuchi Die Patientinnen und Patienten werden hierbei aufgefordert einen roten Lichtpunkt in der Mitte eines homogen beleuchteten Gebietes zu fixieren.

Dieser rote Lichtpunkt wird ca. Balliet et al. Auch Kasten et al. Unter diesen Kindern waren auch neun, bei denen cortical visual impairment diagnostiziert worden ist.

Sonksen et al. Auf einem Computermonitor werden verschiedene visuelle Stimuli dargeboten, die individuell an den entsprechenden Patienten angepasst werden.

Am Ende der Therapie werden die verschiedenen Stimuli gemischt angeboten. Diese Verbesserungen sollen sich sowohl in den Testsituationen als auch im Alltag gezeigt haben.

Tegenthoff Hoyt ; Foley, Gordon Wong und Hoyt konnten z. Ferner werden die Prognoseaussichten infolge von Traumata von Drymalski et al.

Fitzhardinge et al. Vielmehr beurteilen u. Dubowitz et al. So kamen Balliet et al. Durch die physiologische Reifung der Zapfen der Netzhaut, des Sehnerven, des Thalamus, des visuellen Kortex sowie der visuellen Koordinationszentren s.

Roland , S. Dazu wurden mit Hilfe von Bildertechniken sowie elektrophysiologischer Verfahren s.

Der WHO , S. Es fehlen daher Aussagen, anhand deren beurteilt werden kann, welcher Vorgang als Sehvorgang interpretiert wird. Engelhardt, Schipperges , S.

Baillet , der Heidelberger Pupillograph vgl. Duchowny et al. Eken et al. Teilweise war ein Elternteil anwesend, welches das Kind in den Situationen festhielt und passend positionierte vgl.

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